Treatment of Vogt-Koyanagi- Harada's Disease During Pregnancy
| Autor: | Kuniko Tanaka, Nobuyuki Miyata, Satosi Nakamura, Shigeaki Ohno, Kazumi Isobe, Kuniko Tsuda, Hiroko Matoba, Miyuki Sugita |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Fundus Oculi medicine.drug_class Prednisolone Pregnancy Trimester Third Gestational Age Inflammation Disease Immune system Pregnancy medicine Humans Fluorescein Angiography Stage (cooking) Infusions Intravenous Glucocorticoids Fetus business.industry General Medicine medicine.disease eye diseases Surgery Pregnancy Complications Ophthalmology Pregnancy Trimester Second Corticosteroid Female medicine.symptom Abnormality Uveomeningoencephalitic Syndrome business |
| Zdroj: | Japanese Journal of Ophthalmology. 45:177-180 |
| ISSN: | 0021-5155 |
| DOI: | 10.1016/s0021-5155(00)00357-9 |
| Popis: | Background: Caution should be exercised in treating patients with autoimmune diseases during pregnancy. Cases: We successfully treated three cases of Vogt-Koyanagi-Harada's disease (VKH disease) during pregnancy. Observations: In the second trimester (14–27 weeks) of 1 patient, inflammation was mild and could be treated by topical corticosteroid. There is the possibility that her immune response had been modified by pregnancy. Systemic corticosteroid in a high dose was administered to the two cases in the second and third trimesters of pregnancy (28–41 weeks). The severity of inflammation in these 2 patients was similar to that in nonpregnant women. Inflammation subsided immediately without recurrence in all cases. No abnormality was found during the deliveries or in the babies. Conclusions: Treatment for VKH disease during pregnancy should be chosen according to the severity of inflammation, the stage of pregnancy, and the maternal and fetal conditions. |
| Databáze: | OpenAIRE |
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