Antibody mix-and-read assays based on fluorescence intensity probes

Autor:	Binh Vu, Atul Goyal, Ujwal Patil, Richard C. Willson, Vijay Maranholkar, Yanyun Liu, Katerina Kourentzi, James M. Briggs
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Monoclonal antibody Lysis medicine.drug_class Immunology CHO Cells High-performance liquid chromatography Cricetulus Report Cricetinae medicine Immunology and Allergy IGG titer Animals Staphylococcal Protein A affinity peptide high-throughput biology Chemistry Chinese hamster ovary cell productivity screening Molecular biology Fluorescence Immunoglobulin Fc Fragments Molecular Docking Simulation Cell culture biology.protein fluorescence Antibody Fluorescence anisotropy
Zdroj:	mAbs article-version (VoR) Version of Record
ISSN:	1942-0870 1942-0862
Popis:	Antibodies and Fc fusion proteins are a rapidly growing class of pharmaceuticals. Cell culture and purification process development and operation require frequent measurement of product concentrations, commonly by complex enzyme-linked immunosorbent assay and high-performance liquid chromatography methods. Here we report a fast (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b91dd277addd823fdae1202ccf407c7 http://europepmc.org/articles/PMC8525972 Zobrazit plný text záznamu