Dynamic Patterns of Systemic Innate Immunity and Inflammatory Associated Factors in Experimental Caprine Coccidiosis
| Autor: | Seyed Mostafa Razavi, Shabnam Tadayon, Saeed Nazifi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Animal Experimentation Time Factors caprine coccidiosis 040301 veterinary sciences Eimeria caprina Inflammation Eimeria ninakohlyakimovae 0403 veterinary science 03 medical and health sciences Adenosine deaminase medicine Animals Immunologic Factors Animal testing Innate immune system Goat Diseases biology Coccidiosis Goats Acute-phase protein inflammatory factor 04 agricultural and veterinary sciences medicine.disease Immunity Innate 030104 developmental biology Infectious Diseases Eimeria arloingi Immunology Circulatory system biology.protein Parasitology Original Article medicine.symptom systemic innate immunity |
| Zdroj: | The Korean Journal of Parasitology |
| ISSN: | 1738-0006 0023-4001 |
| Popis: | The present study was designed to assess the dynamic patterns of pro-inflammatory cytokines, including IFN-γ, TNF-α, IL-4, IL-6, acute phase protein (α1-acid-glycoprotein, AGP), and an inflammation associated factor (adenosine deaminase; ADA) following experimental caprine coccidiosis. Ten kids aging from 2 to 4 months were infected orally with 5×104 sporulated oocysts and 10 animals served as controls. Blood samples were collected in both groups before infection and at days 3, 7, 14, 21, 28, and 35 post-infection (PI), and the levels of above-mentioned factors were measured. IFN-γ, TNF-α, IL-4, IL-6, AGP, and ADA activities were significantly higher in infected animals from day 7 PI (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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