Hereditary Nephritis Associated with May-Hegglin Anomaly
| Autor: | R. Girot, F. Brivet, M. Maier, C. Gazengel, J. Crosnier, C. Barbanel |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty Bleeding Time Platelet Aggregation Platelet Function Tests Neutrophils Nephritis Hereditary medicine Humans Child business.industry Infant Bone Marrow Examination Syndrome Blood Coagulation Disorders medicine.disease Thrombocytopenia Dermatology Pedigree May–Hegglin anomaly Female Anomaly (physics) business Nephritis Granulocytes |
| Zdroj: | Nephron. 29:59-62 |
| ISSN: | 2235-3186 1660-8151 |
| Popis: | Hereditary nephritis associated with hematologic abnormalities seems to be an exceptional occurrence. We have observed a family which nephritis was combined with May-Hegglin anomaly. A girl and her father suffered from proteinuria; a paternal uncle received kidney graft; a paternal grand aunt died on periodic hemodialysis. The girl, the father and the uncle presented macrothrombocytopenia (40-100 X 10(9)/l, size 4-8 mum) with prolonged bleeding time (which precluded renal biopsy) and cytoplasmic inclusions in neutrophils (Döhle bodies). These hematologic abnormalities characterize the May-Hegglin anomaly. This kind of association has not been reported so far. |
| Databáze: | OpenAIRE |
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