Non-invasive blood pressure measurement in ferrets ( Mustela putorius furo ) using high definition oscillometry
| Autor: | van Zeeland, Y. R.A., Wilde, A., Bosman, I.H., Uilenreef, J. J., Egner, B.I., Schoemaker, N. J., Vogels en bijzondere dieren, LS Anesthesiologie, dCSCA AVR |
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| Přispěvatelé: | Vogels en bijzondere dieren, LS Anesthesiologie, dCSCA AVR |
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine High definition oscillometry 040301 veterinary sciences Butorphanol Diastole Reference ranges Blood Pressure 0403 veterinary science 03 medical and health sciences Reference Values Oscillometry medicine Animals General Veterinary biology business.industry Ferrets Blood Pressure Determination 04 agricultural and veterinary sciences biology.organism_classification 030104 developmental biology Blood pressure Anesthesia Mustela putorius Cuff Midazolam Animal Science and Zoology business Non-invasive blood pressure measurement medicine.drug |
| Zdroj: | Veterinary Journal, 228, 53. Bailliere Tindall Ltd |
| ISSN: | 1090-0233 |
| Popis: | This study was conducted to validate the use of high definition oscillometry (HDO) for non-invasive blood pressure (NIBP) measurements in ferrets and to establish reference ranges for NIBP in minimally sedated, healthy, young adult ferrets (4years of age). The bias, limits of agreement and correlation for HDO compared to direct arterial blood pressure (DABP) measurement were established in 14 anaesthetised ferrets. Measurements were performed at the forelimb, hind limb and tail under hypo- (110mmHg), normo- (110-170mmHg) and hypertensive (170mmHg) conditions. Although HDO correlated well with DABP (r0.90), it showed significant proportional bias, whereby HDO generally underestimated DABP with hyper- and normotensive conditions, and overestimated DABP with hypotensive conditions. Measurements obtained from the hind limb showed higher bias than those obtained from the tail or forelimb (P0.001). Based on the above, and for practical reasons, the tail was selected as the preferred site of cuff placement in ferrets. Subsequently, a cross-over study was performed in 10 ferrets to establish the minimum dose of butorphanol and midazolam needed to successfully obtain NIBP in 100% of cases. Using this dose (0.2mg/kg IM, each), reference intervals for NIBP from 63 healthy, young adult ferrets were established at 95-155mmHg (systolic), 69-109mmHg (mean) and 51-87mmHg (diastolic) arterial pressures. |
| Databáze: | OpenAIRE |
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