Demonstration of antibodies to testicular basement membrane by immunofluorescence in a patient with multiple primary endocrine deficiencies
| Autor: | N. S. Peress, Shadab Ali Khan, G. G. Murthy |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Endocrinology Diabetes and Metabolism Clinical Biochemistry Fluorescent Antibody Technique Immunofluorescence Endocrine System Diseases Biochemistry Antibodies Basement Membrane Endocrinology Internal medicine Testis medicine Endocrine system Humans Hydroxysteroids Aged Basement membrane biology medicine.diagnostic_test Biochemistry (medical) Thyroid Gamma globulin 17-Ketosteroids Seminiferous tubule medicine.anatomical_structure biology.protein Antibody Endocrine gland |
| Zdroj: | The Journal of clinical endocrinology and metabolism. 42(4) |
| ISSN: | 0021-972X |
| Popis: | Circulating antibodies directed against testicular basement membrane and germinal cells are demonstrated in a patient with multiple primary endocrine gland deficiencies involving the thyroid, adrenals, testes, and pernicious anemia. Testicular biopsy revealed focal destruction of seminiferous tubules and interstitial fibrosis. The tubular basement membranes showed sharply positive immunofluorescence when stained with the patient's FITC conjugated gamma globulins. |
| Databáze: | OpenAIRE |
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