Mammographic density: intersection of science, the law, and clinical practice
| Autor: | Scott Hollenbeck, Patricia Keely, Victoria Seewaldt |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Risk
Hormone Replacement Therapy Breast Neoplasms Truth Disclosure Sensitivity and Specificity Epithelium Body Mass Index Ethnicity Humans Breast Mammary Glands Human Early Detection of Cancer Breast Density Clinical Trials as Topic Age Factors General Medicine Magnetic Resonance Imaging United States Extracellular Matrix Tamoxifen Adipose Tissue Connective Tissue Female Collagen Algorithms Mammography |
| Zdroj: | American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. |
| ISSN: | 1548-8756 |
| Popis: | High mammographic density is associated with a two- to sixfold increased risk of breast cancer. Mammographic density can be altered by endogenous and exogenous hormonal factors and generally declines with age. Mammographic density is affected by confounding factors such as age, parity, menopausal status, and body mass index (BMI), thus making interpretation of mammographic density challenging. None of the established means of measuring mammographic density are entirely satisfactory because they are time consuming and/or subjective. Although mammographic density has been shown to predict breast cancer risk, the role of mammographic density in precisely assessing a woman's breast cancer risk over her lifetime and evaluating response to risk-reduction strategies cannot be fully realized until we have a better understanding of the biology that links mammographic density to breast cancer risk. |
| Databáze: | OpenAIRE |
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