Anxiety and Depression in Patients with Traumatic Spinal Cord Injury: A Nationwide Population-Based Cohort Study

Autor: Chung-Han Ho, Jhi-Joung Wang, Shou-Chun Yu, Jinn-Rung Kuo, Sher-Wei Lim, Yow-Ling Shiue, Pei-Hsin Kao
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
030506 rehabilitation
Critical Care and Emergency Medicine
Time Factors
Databases
Factual
Emotions
Poison control
lcsh:Medicine
Social Sciences
Anxiety
Vascular Medicine
Geographical Locations
0302 clinical medicine
Endocrinology
Medicine and Health Sciences
Psychology
Coronary Heart Disease
Public and Occupational Health
Longitudinal Studies
lcsh:Science
Spinal Cord Injury
Depression (differential diagnoses)
Trauma Medicine
Aged
80 and over
education.field_of_study
Multidisciplinary
Trauma Severity Indices
Depression
Hazard ratio
Middle Aged
Socioeconomic Aspects of Health
Neurology
Cohort
Injury Severity Score
Female
medicine.symptom
0305 other medical science
Traumatic Injury
Research Article
Adult
medicine.medical_specialty
Asia
Adolescent
Endocrine Disorders
Population
Cardiology
Taiwan
03 medical and health sciences
Internal medicine
Mental Health and Psychiatry
medicine
Diabetes Mellitus
Humans
education
Spinal Cord Injuries
Aged
business.industry
Mood Disorders
lcsh:R
Biology and Life Sciences
Health Care
Relative risk
Metabolic Disorders
People and Places
Physical therapy
lcsh:Q
business
Neurotrauma
030217 neurology & neurosurgery
Follow-Up Studies
Zdroj: PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0169623 (2017)
ISSN: 1932-6203
Popis: Background Traumatic spinal cord injury (tSCI) may involve new-onset anxiety and depression post-discharge. However, long-term population-based studies have lacked access to follow-up conditions in terms of new-onset anxiety and depression. The objective of this study was to estimate the long-term risk of new-onset anxiety and depression post-discharge. Methods The Longitudinal Health Insurance Database 2000 (LHID2000) from Taiwan’s National Health Insurance Research Database was used in this study. Individuals with tSCI were identified using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnostic codes of 806 and 952 from 1999–2008. The comparison cohort (other health conditions group) was randomly selected from the LHID2000 and was 1:1 matched by age, sex, index year, and comorbidities to reduce the selection bias. All study participants were retrospectively followed for a maximum of 3 years until the end of follow-up, death, or new-onset anxiety (ICD-9-CM: 309.2–309.4) or depression (ICD-9-CM: 296.2, 296.5, 296.82, 300.4, 309.0–309.1, and 311). Persons who were issued a catastrophic illness card for tSCI were categorized as having a severe level of SCI (Injury Severity Score [ISS] ≥16). Poisson regression was used to estimate the incidence rate ratios of anxiety or depression between patients with tSCI and other health conditions. The relative risk of anxiety or depression was estimated using a Cox regression analysis, which was adjusted for potential confounding factors. Results Univariate analyses showed that the tSCI patients (n = 3556) had a 1.33 times greater incidence of new-onset anxiety or depression (95% confidence interval [CI]: 1.12–1.57) compared to the other health conditions group (n = 3556). After adjusting for potential risk factors, the tSCI patients had a significant 1.29-fold increased risk of anxiety or depression compared to the group with other health conditions (95% CI: 1.09–1.53). Individuals with tSCI, including patients who were under the age of 35, patients who were males, patients who had a low income, and patients without a Charlson Comorbidity Index score, all had a higher long-term risk of anxiety or depression than the other health conditions group (IRRs: 1.84, 1.63, 1.29, and 1.39, respectively). For all tSCI patients, those with an Injury Severity Score (ISS) ≥16 had an almost 2-fold higher risk of anxiety or depression (adjusted Hazard Ratio: 1.85; 95% CI: 1.17–2.92) compared to those with ISS
Databáze: OpenAIRE
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