Arg25Pro polymorphism of transforming growth factor-beta1 and its role in the pathogenesis of essential hypertension in Russian population of the Central Chernozem Region
| Autor: | A. M. Shestakov, D. A. Belugin, D. V. Ushachev, O. E. Kolesnikova, Kozhukhov Ma, I. V. Khoroshaya, A. V. Polonnikov, Vladimir P. Ivanov, M. A. Solodilova, L. N. Katargina |
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| Rok vydání: | 2008 |
| Předmět: |
Genetics
Male Polymorphism Genetic Genotype General Medicine Biology Essential hypertension medicine.disease General Biochemistry Genetics and Molecular Biology Russia Pathogenesis Transforming Growth Factor beta1 Gene Frequency Polymorphism (computer science) Hypertension medicine Humans Female Allele Allele frequency Chernozem Transforming growth factor |
| Zdroj: | Bulletin of experimental biology and medicine. 144(1) |
| ISSN: | 0007-4888 |
| Popis: | We studied the relationship between Arg25Pro polymorphism of TGFbeta1 gene and predisposition to essential hypertension in the Russian population of Central Chernozem Region (n=402). An association was found between 25Pro allele and 25ArgPro genotype with low risk of essential hypertension in male individuals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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