Endometrioid Adenocarcinoma with High-Grade Transformation with Serous and Choriocarcinomatous Differentiation - A Case Report

Autor: Hiroe Itami, Eriko Nakagawa, Miho Muraji, Tamotsu Sudo, Chiho Ohbayashi, Kiyoshi Fujiwara, Seiji Kanayama, Sayaka Ueno, Fumi Kawakami, Ryuichiro Nishimura, Hironobu Nishikawa, Satoshi Yamaguchi, Senn Wakahashi, Takashi Yamada
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Journal of Cancer
ISSN: 1837-9664
Popis: A choriocarcinoma component with a malignant tumor is relatively rare. We present a case of an 85-year-old woman with mixed carcinoma, which was endometrioid adenocarcinoma with squamous differentiation, choriocarcinoma and a disseminated peritoneal nodule, which was papillary serous adenocarcinoma. The patient received surgery and conservative treatment. Twenty weeks after surgery, a recurring tumor appeared at the Douglas pouch. Histology showed that the recurring tumor was poorly differentiated carcinoma that was very different from the primary tumor. This case represents an unusual uterine corpus cancer with high-grade transformation with serous and choriocarcinomatous differentiation. This case also demonstrates the capacity of tumor cells to differentiate into divergent elements.
Databáze: OpenAIRE