Obsessive-compulsive symptom dimensions in a population-based, cross-sectional sample of school-aged children
| Autor: | Pedro Gomes de Alvarenga, Euripedes Constantino Miguel, Raony C. Cesar, Marcelo Q. Hoexter, Guilherme V. Polanczyk, Maria Conceição do Rosário, Catherine G. Coughlin, James F. Leckman, Gisele Gus Manfro, Tais Silveira Moriyama, Michael H. Bloch, Albina Rodrigues Torres |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Obsessive-Compulsive Disorder Sample (statistics) Population based Community Health Planning Psychiatric comorbidity Sex Factors Obsessive compulsive Residence Characteristics Epidemiology medicine Humans Family history Child Biological Psychiatry Psychiatric Status Rating Scales School age child Age Factors Family aggregation Psychiatry and Mental health Cross-Sectional Studies Female Psychology EPIDEMIOLOGIA Clinical psychology |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 1879-1379 |
| Popis: | Background Obsessive-compulsive disorder can be expressed as four potentially overlapping obsessive-compulsive symptom (OCS) dimensions (OCSD) (“symmetry/ordering”, “contamination/cleaning”, “aggressive/sexual/religious” and “collecting/hoarding”). In clinical samples, some dimensions are more familial and associated with increased psychiatric comorbidity and malfunctioning. However, data concerning OCS and OCSD are scarce in non-clinical samples, particularly among children. The present study aims to estimate: (1) the prevalence and sex/age distribution of OCS/OCSD in a community-based sample of schoolchildren; (2) the association between OCS and additional clinical factors; and (3) the degree of familial aggregation of OCS/OCSD. Methods OCS and OCSD were evaluated in 9937 Brazilian school-children (6–12 years-old) and their biological relatives using the Family History Screen. Data analyses included gradient estimated equations and post-hoc tests. Results We included data on 9937 index-children, 3305 siblings (13–18 years-old), and 16,218 parents. Biological mothers were the informants in 87.6% of the interviews. OCS were present in 14.7% of the index-children; 15.6% of their siblings; 34.6% of their mothers and 12.1% of their fathers. The prevalence of OCS and each of the OCSD gradually increased from ages 6 to 12 years. Overall, OCS in children were associated with the presence of other psychiatric symptoms, as well as behavioral/school impairment. OCS and each of the four OCSD aggregated significantly within families. Conclusions OCS are prevalent and associated with psychiatric symptoms and clinical impairment among school-aged children. OCSD aggregate within families in a dimension-specific fashion. These findings suggest a natural continuum between OCS and OCD with regard to their dimensional character. |
| Databáze: | OpenAIRE |
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