Optimal levels of DHEA for pregnancy may be reduced by antibiotics

Autor:	James M. Howard
Rok vydání:	2017
Předmět:	0301 basic medicine endocrine system medicine.medical_specialty medicine.drug_class Antibiotics Dehydroepiandrosterone Fertilization in Vitro 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Dehydroepiandrosterone sulfate Pregnancy Internal medicine polycyclic compounds medicine Humans Letters skin and connective tissue diseases 030219 obstetrics & reproductive medicine biology business.industry General Medicine medicine.disease Anti-Bacterial Agents 030104 developmental biology Endocrinology chemistry biology.protein Female business human activities Arylsulfatase hormones hormone substitutes and hormone antagonists
Zdroj:	CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 189(30)
ISSN:	1488-2329
Popis:	I suggest that the basis of the findings of Muanda and colleagues in their CMAJ article[1][1] is reduced dehydroepiandrosterone (DHEA) (i.e., antibiotics reduce arylsulfatase, which reduces availability of DHEA). Dehydroepiandrosterone sulfate (DHEAS) is the precursor of the active molecule, DHEA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5e5a52e70803b41cd6af3de5c7e235 https://pubmed.ncbi.nlm.nih.gov/28760839 Zobrazit plný text záznamu