Radiation-Induced Sarcoma After Heterotopic Ossification Prophylaxis: A Case Report
| Autor: | Yasser R. Farid, Nasma K Majeed, Benjamin E. Onderdonk, Grace Guzman, Christina H. Son, Philip P. Connell, David M. Rosenberg |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
030506 rehabilitation
medicine.medical_specialty Neoplasms Radiation-Induced medicine.medical_treatment Periprosthetic Soft Tissue Neoplasms 03 medical and health sciences 0302 clinical medicine Postoperative Complications Medicine Humans Orthopedics and Sports Medicine Arthroplasty Replacement Knee Pathological Radiotherapy business.industry Ossification Heterotopic Sarcoma Middle Aged medicine.disease Single fraction Radiation therapy Radiation induced sarcoma Surgery Heterotopic ossification Female Radiology 0305 other medical science Complication business Knee Prosthesis 030217 neurology & neurosurgery |
| Zdroj: | JBJS case connector. 9(4) |
| ISSN: | 2160-3251 |
| Popis: | CASE Heterotopic ossification (HO) is a pathological formation of bone in nonosseous tissue and is a common complication of orthopaedic procedures. Radiotherapy is often used to prevent HO despite the small risk of secondary malignancy. Here, we report a case of a patient who developed a periprosthetic, radiation-induced sarcoma after delivery of a single fraction of 7 Gy for HO prophylaxis. This sarcoma was found to lie entirely within the treatment field and occurred within 5 years of radiation. CONCLUSION Appropriate counseling regarding radiation-induced sarcoma formation should be provided to patients considering radiotherapy for this HO prophylaxis. |
| Databáze: | OpenAIRE |
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