Efficient synthesis of novel bis(dihydropyrano[2,3c]pyrazoles), bis(4H-chromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality

Autor: Ismail A. Abdelhamid, Amna M. Abdella, Holger Butenschön, Amr M. Abdelmoniem, Ahmed H. M. Elwahy
Rok vydání: 2019
Předmět:
Zdroj: Arkivoc 4 (2019)
ARKIVOC, Vol 2019, Iss 6, Pp 306-324 (2019)
ISSN: 1551-7012
DOI: 10.24820/ark.5550190.p011.071
Popis: A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles), bis(4H-chromene-3-carbonitriles) and bis(dihydropyrano[3,2-c]chromenes), which are linked to aliphatic spacers via amide linkages was achieved via multicomponent reactions (MCR) of the appropriate bis-aldehyde with two equivalents of both of malononitrile and 3-methylpyrazol-5-one, dimedone or 4-hydroxycoumarin in a basic solution.
Databáze: OpenAIRE