Immunoscintigraphy and distribution study of experimental tumours using131I-labelled anti-fibrinogen antibodies
| Autor: | H. Kopřivová, Dienstbier Z, Sůrová H, Svihovcová P, Novák F, A. Glagolicova |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Pathology
medicine.medical_specialty Gallium Radioisotopes Scintigraphy Fibrinogen Antibodies Fibrin Immunoscintigraphy Fibrin Fibrinogen Degradation Products Iodine Radioisotopes medicine Animals Distribution (pharmacology) Tissue Distribution Radiology Nuclear Medicine and imaging Radionuclide Imaging Sarcoma Yoshida biology medicine.diagnostic_test business.industry Rats Inbred Strains General Medicine Rats Immunoglobulin G biology.protein Female Antibody business Neoplasm Transplantation medicine.drug |
| Zdroj: | European Journal of Nuclear Medicine. 9:478-481 |
| ISSN: | 1619-7089 0340-6997 |
| DOI: | 10.1007/bf00563173 |
| Popis: | 131I-labelled antibodies to the fragment E of human fibrin, anti-rat fibrinogen, non-immune rabbit IgG and 67Ga-citrate were used for scintigraphy and distribution studies in experimental tumours in rats. The best visualisation was achieved with 131I-labelled anti-rat fibrinogen antibodies at intervals longer than 48 h after administration. Tumour to tissue ratios found in distribution studies performed formed more than 48 h after administration were higher in most examined tissues when using 131I-labelled antibodies than those obtained with 67Ga-citrate. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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