Esophageal motility after laparoscopic sleeve gastrectomy
| Autor: | Constantine Chatzitheofilou, Dimitris Zacharoulis, Spyros P. Potamianos, Fotios D. Tsiopoulos, Eleni Sioka, Dimitris Papamargaritis, George Tzovaras |
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| Rok vydání: | 2017 |
| Předmět: |
030209 endocrinology & metabolism
Regurgitation (circulation) 03 medical and health sciences 0302 clinical medicine Statistical significance gastro esophageal reflux medicine otorhinolaryngologic diseases Esophagus Peristalsis Original Research esophagus Laparoscopic sleeve gastrectomy Clinical and Experimental Gastroenterology business.industry Gastroenterology Reflux Heartburn manometry Confidence interval obesity surgery medicine.anatomical_structure motility Anesthesia 030211 gastroenterology & hepatology medicine.symptom laparoscopic sleeve gastrectomy business |
| Zdroj: | Clinical and Experimental Gastroenterology |
| ISSN: | 1178-7023 |
| Popis: | Eleni Sioka,1 George Tzovaras,1 Fotios Tsiopoulos,2 Dimitris Papamargaritis,1 Spyros Potamianos,2 Constantine Chatzitheofilou,1 Dimitris Zacharoulis1 1Department of Surgery, 2Department of Gastroenterology, University Hospital of Larissa, University of Thessaly, Larissa, Greece Background: Laparoscopic sleeve gastrectomy (LSG) modifies the upper gastrointestinal tract motility. Controversial data currently exist. The aim of the study was to evaluate esophageal motility before and after LSG.Patients and methods: Morbid obese patients scheduled for LSG underwent reflux symptoms evaluation and manometry preoperatively and postoperatively. The preoperative and postoperative results were compared and analyzed.Results: Eighteen patients were enrolled. Heartburn and regurgitation improved in 38.9% and 11.1% of the patients, but deteriorated in 11.1% and 27.8% of the patients, respectively. Lower esophageal sphincter (LES) total length decreased postoperatively (p=0.002). Resting and residual pressures tended to decrease postoperatively (mean difference [95% confidence interval]: −4 [−8.3/0.2] mmHg, p=0.060; −1.4 [−3/0.1] mmHg, p=0.071, respectively). Amplitude pressure decreased from 95.7±37.3 to 69.8±26.3 mmHg at the upper border of LES (p=0.014), and tended to decrease at the distal esophagus from 128.5±30.1 to 112.1±35.4 mmHg (p=0.06) and mid-esophagus from 72.7±34.5 to 49.4±16.7 mmHg (p=0.006). Peristaltic normal swallow percentage increased from 47.2±36.8 to 82.8±28% (p=0.003). Postoperative regurgitation was strongly negatively correlated with LES total length (Spearman’s r=−0.670). When groups were compared according to heartburn status, statistical significance was observed between the groups of improvement and deterioration regarding postoperative residual pressure and postoperative relaxation (p |
| Databáze: | OpenAIRE |
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