Autopsy case of primary choriocarcinoma of the urinary bladder

Autor: Yuming Zhang, Masayoshi Iwasaki, Taketoshi Kushida, Tadashi Matsuda, Akiharu Okamura, Susumu Ikehara, Motohiko Sugi, Hideki Sugao, Miyo Matsumura, Yasushi Koike, Hiromi Mukaide, Yasushi Adachi, Yasuhiro Suzuki, Kouei Muguruma, Keizo Minamino, Masato Watanabe, Jianfeng Wang, Keiji Nakano
Rok vydání: 2005
Předmět:
Zdroj: Pathology International. 55:216-222
ISSN: 1440-1827
1320-5463
DOI: 10.1111/j.1320-5463.2005.01814.x
Popis: Choriocarcinomas usually develop in the uterus and ovaries in the female, being extremely rare in the extragenital organs in the male. Extragenital choriocarcinomas in the male usually develop in the mediastinum or retroperitoneum. The frequency of choriocarcinoma in the urinary bladder is extremely low. The purpose of the present paper was to report an autopsy case of choriocarcinoma in the urinary bladder in the male. An 81-year-old male patient with macrohematuria was first diagnosed with transitional cell carcinoma (TCC). At autopsy a hemorrhagic necrotic tumor, which was found in the urinary bladder with metastatic lesions in the lungs, was diagnosed as choriocarcinoma microscopically. There was no evidence for choriocarcinoma derived from any other organs than the urinary bladder, although there were metastatic lesions in both lungs and the direct invasion into the prostate. From these findings it is concluded that the tumor was a primary choriocarcinoma in the urinary bladder in a male patient. Choriocarcinoma of the urinary bladder is very rare, but the prognosis is extremely poor in comparison with TCC even in the urinary bladder. Therefore, it is essential to clearly discriminate between choriocarcinomas and TCC.
Databáze: OpenAIRE