Two types of haemophilia (A+ and A-): a study of 48 cases

Autor:	Kathryn Cobb, R. Borrett, M.E. Haddon, Rosemary Biggs, K. W. E. Denson
Rok vydání:	1969
Předmět:	Male medicine.medical_specialty Factor VIII business.industry Haemophilia A Hematology medicine.disease Haemophilia Hemophilia A Antibodies Surgery Antigen-Antibody Reactions von Willebrand Diseases hemic and lymphatic diseases Internal medicine Antibody Formation medicine Humans business
Zdroj:	British journal of haematology. 17(2)
ISSN:	0007-1048
Popis:	Summary. The inhibitor-neutralizing ability of plasma and Factor-VIII concentrates from a group of 48 haemophilic patients and 30 normal persons has been studied. Factor-VIII inhibitors were neutralized by the material from four of the haemophilic patients and all the normal subjects. The material from the larger group of 44 haemophilic patients showed no significant inhibitor-neutralizing ability. The former group have been designated Haemophilia A+ because of the presence of material antigenically related to Factor VIII, and the latter group Haemophilia A− because of the lack of such material.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4141a28f699bb9e77a9d988321d615 https://pubmed.ncbi.nlm.nih.gov/5306640 Zobrazit plný text záznamu Plný text