An approach for quantitative mapping of synaptic periactive zone architecture and organization

Autor:	Steven J. Del Signore, Margalit G. Mitzner, Anne M. Silveira, Thomas G. Fai, Avital A. Rodal
Rok vydání:	2023
Předmět:	Cell Biology Molecular Biology
Zdroj:	Molecular Biology of the Cell. 34
ISSN:	1939-4586 1059-1524
DOI:	10.1091/mbc.e22-08-0372
Popis:	Following exocytosis at active zones, synaptic vesicle membranes and membrane-bound proteins must be recycled. The endocytic machinery that drives this recycling accumulates in the periactive zone (PAZ), a region of the synapse adjacent to active zones, but the organization of this machinery within the PAZ, and how PAZ composition relates to active zone release properties remains unknown. The PAZ is also enriched for cell adhesion proteins, but their function at these sites is poorly understood. Here, using Airyscan and STED imaging of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b32503a30febef857a8ed3a98f14123 https://doi.org/10.1091/mbc.e22-08-0372 Zobrazit plný text záznamu