Cesarean section and risk of allergies in Ecuadorian children: A cross-sectional study

Autor:	Tamar Kinaciyan, Amelie Gorris, Gabriela Bustamante, Katharina A. Mayer, Gerhard J. Zlabinger
Rok vydání:	2020
Předmět:	0301 basic medicine lcsh:Immunologic diseases. Allergy Male Allergy Pediatrics medicine.medical_specialty Cross-sectional study Immunology Breastfeeding 03 medical and health sciences 0302 clinical medicine rhinitis medicine Immunology and Allergy Humans Child Asthma Original Research Pregnancy food allergy atopic dermatitis business.industry Cesarean Section Atopic dermatitis Odds ratio asthma medicine.disease Delivery mode Rhinitis Allergic 030104 developmental biology Cross-Sectional Studies Child Preschool Female Ecuador business lcsh:RC581-607 environment and hygiene hypothesis 030215 immunology
Zdroj:	Immunity, Inflammation and Disease Immunity, Inflammation and Disease, Vol 8, Iss 4, Pp 763-773 (2020)
ISSN:	2050-4527
Popis:	Background Studies have shown an association between cesarean section (CS) and increased prevalence of childhood allergic diseases. While these observations have been consistent in industrialized countries, evidence from developing countries is limited. Objective To assess the association between the mode of delivery and allergic diseases in children aged 3–12 years in Quito, Ecuador. Methods In this cross‐sectional study, parents were surveyed using an anonymous, standardized questionnaire from the International Study of Asthma and Allergies in Childhood project to assess the presence of asthma, allergic rhinitis, atopic dermatitis, and food allergies in their children. The children's age, sex, birthplace, delivery mode (CS/vaginal), socioeconomic status, and ethnicity were recorded. Other parameters included gestational age, breastfeeding, smoking status during pregnancy, and parental allergic diseases. Results After adjusting for confounding factors, children delivered via CS were found to have a higher risk of wheezing (odds ratio [OR] = 4.12, 95% confidence interval [CI]: 1.43–11.89), physician‐diagnosed asthma (OR = 24.06; 95% CI: 1.98–292.3), and pimples, or eczema with the itching for 6 months (OR = 2.65; 95% CI: 1.06–6.61) than children delivered vaginally. No association was found between the delivery mode and rhinitis or food allergies. After stratifying by socioeconomic status, CS was only associated with allergic disorders in children of medium/high socioeconomic backgrounds. Conclusions As seen in industrialized settings, children born by CS in nonindustrialized countries have an increased risk of developing allergic disorders including asthma and dermatitis, compared to those delivered vaginally. Study enrollment flowchart. Parents of 400 children did participate in the present study and answered 189 questionnaires. The response rate was 47.25%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2e43604dd02711414803f86fce0fd4 https://pubmed.ncbi.nlm.nih.gov/33128350 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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