The Value of Power Doppler Ultrasound in Patients With Rheumatoid Arthritis in Clinical Remission: Reclassifying Disease Activity?
| Autor: | Santiago Ruta, Enrique R. Soriano, Facundo Vergara, Javier Rosa, Ricardo García-Mónaco, Josefina Marin |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study Severity of Illness Index Arthritis Rheumatoid Disease activity 03 medical and health sciences 0302 clinical medicine Internal medicine Severity of illness medicine Humans In patient 030212 general & internal medicine Aged 030203 arthritis & rheumatology business.industry Remission Induction Ultrasound Ultrasonography Doppler General Medicine Middle Aged medicine.disease Rheumatology Cross-Sectional Studies Rheumatoid arthritis Female business Rheumatism |
| Zdroj: | Reumatología Clínica (English Edition). 14:202-206 |
| ISSN: | 2173-5743 |
| Popis: | The aim of the present study was to describe the ultrasound (US) findings in patients with rheumatoid arthritis (RA) in clinical remission, and to evaluate the ability of power Doppler (PD) US to reclassify disease activity in these patients.We included consecutive patients with RA according to 2010 American College of Rheumatology/European League Against Rheumatism criteria, who were in clinical remission by the Disease Activity Score (DAS282.6). Twenty joints of both hands were assessed by US. PD signal was evaluated on a semi-quantitative scale from 0 to 3. Three different US-modified DAS28 (US-DAS28) were constructed, replacing the clinical swollen joint count by the PD US joint count using PD score ≥1, ≥2 or ≥3, respectively.Eighty-six patients were included. Twenty-three (26.7%) patients had at least one joint with abnormal US-positive PD signal. Thirteen percent of patients were reclassified to low disease activity by applying the US-DAS28 when joints were considered active with a PD signal ≥1; 12%, when a PD signal ≥2 was considered, and 2% of the patients were reclassified when a PD score of 3 was considered. No patients were reclassified to a level of moderate or high activity applying US-DAS28.Although around a quarter of patients with RA in clinical remission showed PD US features indicating residual activity, only a small percentage were reclassified to a state of low activity and none to a level of moderate or high activity, applying the proposed US-DAS28. |
| Databáze: | OpenAIRE |
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