Subtle neuropsychiatric symptoms of glioblastoma multiforme misdiagnosed as depression
| Autor: | Jill N Frodey, Raphael J. Leo, Matthew L Ruggieri |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Neurocognitive Disorders Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Quality of life Neuroimaging medicine Humans Depression (differential diagnoses) Depressive Disorder Brain Neoplasms business.industry General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Reminder of Important Clinical Lesson 030220 oncology & carcinogenesis Central nervous system cancer Diagnostic assessment Psychiatric disturbances Clinical case Glioblastoma business 030217 neurology & neurosurgery |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2019-233208 |
| Popis: | Glioblastoma multiforme (GBM) is the most common of the aggressive primary brain tumours arising in adults and has a dire prognosis. Neuropsychiatric symptoms can vary significantly among afflicted persons; psychiatric disturbances may be the predominant presenting symptoms. Distinguishing between functional psychiatric disorders, particularly depression, from other subtle neuropsychiatric disturbances that may accompany GBM can be challenging. The authors present a clinical case and review of the literature in an attempt to highlight the special considerations that should be taken into account when evaluating patients who present with late-onset or atypical symptoms, refractory psychiatric symptoms, or subtle neurological disturbances signalling the need for diagnostic assessment, particularly neuroimaging, for the presence of a tumour. Early diagnosis is critical for improvement in quality of life. |
| Databáze: | OpenAIRE |
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