New Delhi Metallo-Beta-Lactamase (NDM-1)-Producing Klebsiella Pneumoniae Isolated from a Burned Patient
| Autor: | Paola Bocanegra-Ibarias, Esteban Gonzalez-Diaz, Eduardo Rodríguez-Noriega, Santiago Petersen-Morfin, Rayo Morfin-Otero, S. Esparza-Ahumada, Héctor R. Pérez-Gómez, Elvira Garza-González, Gabriel Amezcua-Salazar, Gerardo León-Garnica |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Isolation (health care) Klebsiella pneumoniae medicine.drug_class Burn Units 030106 microbiology Antibiotics Bacteremia Drug resistance medicine.disease_cause beta-Lactamases Klebsiella Pneumoniae Microbiology 03 medical and health sciences Fatal Outcome Antibiotic resistance Drug Resistance Multiple Bacterial Humans Medicine Cross Infection biology business.industry Pseudomonas aeruginosa Articles General Medicine medicine.disease biology.organism_classification Anti-Bacterial Agents Klebsiella Infections Staphylococcus aureus Genes MDR Burns business |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| DOI: | 10.12659/ajcr.903992 |
| Popis: | Patient: Male, 32 Final Diagnosis: NDM-1-producing Klebsiella pneumoniae • bacteremia Symptoms: Fever Medication: — Clinical Procedure: None Specialty: Infectious Diseases Objective: Diagnostic/therapeutic accidents Background: Infections affecting burn patients are frequently caused by Staphylococcus aureus, Pseudomonas aeruginosa, and Enterobacteriaceae species. Infections with these pathogens have become increasingly difficult to treat due to evolving antibiotic resistance mechanisms, including the production of carbapenemases. Case Report: The present case report describes the evolution of a burn patient with polymicrobial healthcare-associated burn infections, including a bloodstream infection due to an emergent multidrug-resistant New Delhi metallo-beta-lactamase (NDM-1)-producing Klebsiella pneumoniae. During hospitalization, initial antibiotic treatment eradicated some of the infecting species. Newer isolates were found to be multidrug-resistant and required unique antibiotic combinations. The patient’s condition continued to deteriorate after the isolation of multidrug-resistant P. aeruginosa and NDM-1-positive K. pneumoniae from the blood. Conclusions: This case report illustrates the need for adequate antibiotic therapies in burn patients with subsequent infections due to a carbapenemase-producing multidrug-resistant bacteria. The potential danger of new bacterial pathogens should be considered in this group of susceptible patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|