Quality of Life, Pulmonary Function, and Tomographic Scan Abnormalities After ARDS
| Autor: | Ferran Torres, Oriol Roca, Ferran Morell, Esther Pallisa, Joan R. Masclans, Xavier Muñoz, Jordi Rello |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty ARDS Time Factors Critical Illness Health Status Population Critical Care and Intensive Care Medicine Pulmonary function testing Quality of life Internal medicine medicine Humans Respiratory function education Prospective cohort study Aged Respiratory Distress Syndrome education.field_of_study business.industry Case-control study Middle Aged medicine.disease humanities Respiratory Function Tests Surgery Nottingham Health Profile Case-Control Studies Quality of Life Female Tomography X-Ray Computed Cardiology and Cardiovascular Medicine business human activities Follow-Up Studies |
| Zdroj: | Chest. 139:1340-1346 |
| ISSN: | 0012-3692 |
| Popis: | Background ARDS can produce a loss of lung function with persistent sequelae. This study aimed to evaluate health-related quality of life (HRQL) in survivors of ARDS compared with a healthy reference population and to determine the middle/long-term radiographic abnormalities and functional status, as well as their relation to observed HRQL, in these patients. Methods This was a prospective study carried out in three ICUs. HRQL in patients was determined with the Nottingham Health Profile immediately after ARDS diagnosis and 6 months after diagnosis. Patients underwent complete respiratory function testing, chest CT scan study, and the 6-min walk test. Results Follow-up was conducted in 38 patients with ARDS. Survivors of ARDS presented a poorer overall HRQL vs the general population, mainly because of lower scores in the dimensions related to mobility, energy, and social isolation. Limitations in daily life activities were documented in 40%. Respiratory function was altered in 67%, with a restrictive respiratory pattern in 58%. Radiologic study disclosed alterations in 76% (mainly reticular pattern). Patients were able to cover only 366 m (318-411 m) in the 6-min walk test and had a minimum pulse oximetry of 93% (90%-94%). A significant correlation was documented between the overall quality of life at first and at 6 months (r = 0.68, P Conclusions Survivors of ARDS after 6 months had a poorer HRQL than the healthy population and showed mild radiographic and functional involvement. Early HRQL study in these patients enabled early detection of those who would present more long-term HRQL morbidity. |
| Databáze: | OpenAIRE |
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