Synthetic Approaches to the New Drugs Approved During 2015
| Autor: | Christopher J. O’Donnell, Carolyn A. Leverett, Sarah J. Fink, Kevin K.-C. Liu, Hong X. Ding, Andrew C. Flick, Robert E. Kyne |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
Chemistry Anti-Inflammatory Agents Non-Steroidal Antineoplastic Agents Cardiovascular Agents Chemistry Techniques Synthetic Computational biology Pharmacology 01 natural sciences 0104 chemical sciences 03 medical and health sciences 0302 clinical medicine Anti-Infective Agents Gastrointestinal Agents Pharmaceutical Preparations 030220 oncology & carcinogenesis Drug Discovery Hypoglycemic Agents Molecular Medicine Receptors Thrombopoietin Central Nervous System Agents |
| Zdroj: | Journal of Medicinal Chemistry. 60:6480-6515 |
| ISSN: | 1520-4804 0022-2623 |
| Popis: | New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 29 new chemical entities (NCEs) that were approved for the first time in 2015. |
| Databáze: | OpenAIRE |
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