Corynebacterium ulcerans infection of the lung mimicking the histology of Churg-Strauss syndrome
| Autor: | Osamu Matsuno, Eishi Miyazaki, Ryuichi Takenaka, Tadao Nakano, Kiyofumi Ohkusu, Masaru Ando, Takayuki Ezaki, Toshihide Kumamoto, Shin-ichi Nureki |
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| Rok vydání: | 2007 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Pathology medicine.medical_specialty medicine.drug_class Antibiotics Video Recording Churg-Strauss Syndrome Corynebacterium Critical Care and Intensive Care Medicine Diagnosis Differential Corynebacterium ulcerans Bronchoscopy medicine Eosinophilia Humans Pulmonary Eosinophilia Lung Corynebacterium Infections business.industry Respiratory disease Histology Eosinophil Middle Aged medicine.disease respiratory tract diseases medicine.anatomical_structure medicine.symptom Cardiology and Cardiovascular Medicine Vasculitis business Tomography X-Ray Computed |
| Zdroj: | Chest. 131(4) |
| ISSN: | 0012-3692 |
| Popis: | We report the first case of pulmonary Corynebacterium ulcerans infection mimicking Churg-Strauss syndrome (CSS). Productive cough, fever, general fatigue, and weight loss developed in a 50-year-old man. Laboratory data revealed prominent eosinophilia and elevated serum IgE. On chest images, multiple nodules and cavities were predominantly detected in the right lung. Histopathologic examination showed necrotizing granulomas and vasculitis with massive eosinophilic infiltration identical to the findings seen in CSS; however, clusters of Gram-positive, coryneform rods were observed in the alveolar spaces. A toxigenic strain of C ulcerans was isolated from lung tissue. The patient was treated with antibiotics, and a favorable clinical course ensued. |
| Databáze: | OpenAIRE |
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