Microbiology of combat-related extremity wounds: Trauma Infectious Disease Outcomes Study
| Autor: | Timothy J. Whitman, Lauren Greenberg, Laveta Stewart, Joseph L Petfield, Margot Krauss, William P. Bradley, David R. Tribble, Qilu Yu, Dana M Blyth, Dan Lu, Katrin Mende, Faraz Shaikh |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Polymicrobial infection 030106 microbiology Article Microbiology 03 medical and health sciences 0302 clinical medicine Anti-Infective Agents Humans Medicine 030212 general & internal medicine Bacteria Coinfection business.industry Fungi Drug Resistance Microbial Bacterial Infections General Medicine Combat casualty United States Military Personnel Treatment Outcome Infectious Diseases Mycoses Infectious disease (medical specialty) Wound Infection business |
| Zdroj: | Diagn Microbiol Infect Dis |
| ISSN: | 0732-8893 |
| DOI: | 10.1016/j.diagmicrobio.2018.12.008 |
| Popis: | We present extremity wound microbiology data from 250 combat casualties (2009–2012). Confirmed extremity wound infections (EWIs) were based on clinical and laboratory findings. Suspected EWIs had isolation of organisms from wound cultures with associated signs/symptoms not meeting clinical diagnostic criteria. Colonized wounds had organisms isolated without any infection suspicion. A total of 335 confirmed EWIs (131 monomicrobial and 204 polymicrobial) were assessed. Gram-negative bacteria were predominant (57% and 86% of monomicrobial and polymicrobial infections, respectively). In polymicrobial infections, 61% grew only bacteria, while 30% isolated bacteria and mold. Multidrug resistance was observed in 32% of isolates from first monomicrobial EWIs ±3 days of diagnosis, while it was 44% of isolates from polymicrobial EWIs. Approximately 96% and 52% of the suspected and colonized wounds, respectively, shared ≥1 organism in common with the confirmed EWI on the same patient. Understanding of combat-related EWIs can lead to improvements in combat casualty care. |
| Databáze: | OpenAIRE |
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