Association of Symptomatic Acute Human Parvovirus B19 Infection with Human Leukocyte Antigen Class I and II Alleles

Autor:	William E R Ollier, Jonathan R. Kerr, Wendy Thomson, Kay V. Poulton, Derek L. Mattey
Rok vydání:	2002
Předmět:	Adult Male musculoskeletal diseases Adolescent viruses Genes MHC Class II Molecular Sequence Data Genes MHC Class I Human leukocyte antigen Major histocompatibility complex Parvoviridae Infections Gene Frequency Parvovirus B19 Human medicine HLA-B Antigens Humans Immunology and Allergy Amino Acid Sequence Child Alleles Aged Parvoviridae biology Parvovirus Parvovirus infection virus diseases HLA-DR Antigens Odds ratio Middle Aged biology.organism_classification medicine.disease Hypervariable region Infectious Diseases Acute Disease Immunology biology.protein Female HLA-DRB1 Chains
Zdroj:	The Journal of Infectious Diseases. 186:447-452
ISSN:	1537-6613 0022-1899
Popis:	To determine the effect of the major histocompatibility complex on the development of symptoms during acute human parvovirus B19 infection, we compared human leukocyte antigen (HLA) class I and II alleles in 36 patients with symptomatic acute B19 infection with those in >900 control subjects from northwestern England. The frequency of each of HLA-DRB1*01 (P=.016), DRB1*04 (P=.007), and DRB1*07 (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0f2096df0a18ddfa0bfd924863aa4c https://doi.org/10.1086/341947 Zobrazit plný text záznamu