Eye Velocity Gain Fields in MSTd During Optokinetic Stimulation
Autor: | Michael J. Mustari, Ulrich Büttner, Stefan Glasauer, Lukas Brostek |
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Rok vydání: | 2014 |
Předmět: |
Visual perception
genetic structures Cognitive Neuroscience Information Theory Stimulus (physiology) Smooth pursuit Cellular and Molecular Neuroscience Parietal Lobe Animals Eye Movement Measurements Neurons Eye movement Efference copy Signal Processing Computer-Assisted Articles Optokinetic reflex Medial superior temporal area Macaca mulatta Pursuit Smooth Visual Perception Neural Networks Computer Psychology Microelectrodes Neuroscience Photic Stimulation |
Zdroj: | Cerebral Cortex. 25:2181-2190 |
ISSN: | 1460-2199 1047-3211 |
Popis: | Lesion studies argue for an involvement of cortical area dorsal medial superior temporal area (MSTd) in the control of optokinetic response (OKR) eye movements to planar visual stimulation. Neural recordings during OKR suggested that MSTd neurons directly encode stimulus velocity. On the other hand, studies using radial visual flow together with voluntary smooth pursuit eye movements showed that visual motion responses were modulated by eye movement-related signals. Here, we investigated neural responses in MSTd during continuous optokinetic stimulation using an information-theoretic approach for characterizing neural tuning with high resolution. We show that the majority of MSTd neurons exhibit gain-field-like tuning functions rather than directly encoding one variable. Neural responses showed a large diversity of tuning to combinations of retinal and extraretinal input. Eye velocity-related activity was observed prior to the actual eye movements, reflecting an efference copy. The observed tuning functions resembled those emerging in a network model trained to perform summation of 2 population-coded signals. Together, our findings support the hypothesis that MSTd implements the visuomotor transformation from retinal to head-centered stimulus velocity signals for the control of OKR. |
Databáze: | OpenAIRE |
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