Moderate aerobic exercise training for improving reproductive function in infertile patients: A randomized controlled trial
Autor: | Bakhtyar Tartibian, Behzad Hajizadeh Maleki |
---|---|
Rok vydání: | 2017 |
Předmět: |
Adult
Male 0301 basic medicine Infertility Immunology Physiology Inflammation Semen Dinoprost medicine.disease_cause Biochemistry law.invention Andrology 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Malondialdehyde medicine Humans Immunology and Allergy Aerobic exercise Exercise Molecular Biology Infertility Male 030219 obstetrics & reproductive medicine biology Superoxide Dismutase business.industry Hematology Catalase medicine.disease Exercise Therapy Pregnancy rate 030104 developmental biology biology.protein Cytokines medicine.symptom Reactive Oxygen Species business Oxidative stress |
Zdroj: | Cytokine. 92:55-67 |
ISSN: | 1043-4666 |
DOI: | 10.1016/j.cyto.2017.01.007 |
Popis: | This study investigated for the first time the changes in seminal markers of inflammation, oxidative stress status, semen parameters, sperm DNA integrity as well as pregnancy rate following 24weeks of moderate aerobic exercise in infertile patients. A total of 1026 sedentary men (aged 25-40years) attending the infertility clinic with history of more than one year of infertility, were screened and 419 were randomized to either exercise (EX, n=210) or non-exercise (NON-EX, n=209) groups. Exercise training favorably attenuated seminal markers of both inflammation (IL-1β, IL-6, IL-8, and TNF-α) and oxidative stress (ROS, MDA, 8-Isoprostane) as well as enhanced antioxidant defense system (SOD, catalase and TAC) (P |
Databáze: | OpenAIRE |
Externí odkaz: |