Supplementary Data from Rare BRIP1 Missense Alleles Confer Risk for Ovarian and Breast Cancer

Autor:	Paul J. Goodfellow, Elizabeth M. Swisher, Scott H. Kaufmann, Marcy E. Richardson, Marc R. Radke, Rachel Doberstein, Jessica L. Gillespie, Jennifer Ivanovich, Cassandra L. Moyer
Rok vydání:	2023
DOI:	10.1158/0008-5472.22424934
Popis:	Supplementary methods; FS1: BRIP1 nonsense and frameshift mutations; FS2: BRIP1 expression in CRISPR cell lines; FS3: hydroxyurea and TMPyP4 challenge; FS4: HEK293TN CRISPR cell lines; FS5: HeLa stable clone rescues; FS6: Transient rescue screening assay; FS7: Degradation of missense mutant proteins; TS1: List of BRIP1 missense variants identified in cohorts
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af6b2e903081893e9042748bb7176ad https://doi.org/10.1158/0008-5472.22424934 Zobrazit plný text záznamu