Behavior of 3,4-endiol form of 2,3-diketo-gulono-.DELTA.-lactone formed from dehydro-L-ascorbic acid in deoxygenated and neutral solution
| Autor: | Atsushi Kawajiri, Naofumi Morita, Kunihiko Nakata, Masanosuke Takagi |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
chemistry.chemical_classification
Magnetic Resonance Spectroscopy Nutrition and Dietetics Linoleic acid 2 3-Diketogulonic Acid Sugar Acids Medicine (miscellaneous) Ascorbic Acid Buffer solution Hydrogen-Ion Concentration Ascorbic acid Dehydroascorbic Acid Medicinal chemistry Solutions chemistry.chemical_compound chemistry Yield (chemistry) Organic chemistry Lipid Peroxidation Oxidation-Reduction Chromatography High Pressure Liquid Lactone |
| Zdroj: | Journal of Nutritional Science and Vitaminology. 35:61-70 |
| ISSN: | 1881-7742 0301-4800 |
| DOI: | 10.3177/jnsv.35.61 |
| Popis: | The formation of L-ascorbic acid (AsA) was observed when dehydro-L-ascorbic acid (DHA) was dissolved in neutral buffer solutions under N2 bubbling at room temperature. The reduction of DHA was done with the lactonized compound of 2,3-diketo-L-gulonic acid (DKG), that is, the 3,4-endiol form of 2,3-diketo-gulono-delta-lactone (3,4-End DKGL). 3,4-End DKGL was formed from DHA or DKG (yield about 10%) under N2 bubbling in neutral buffer solution (pH 7.2). This material was not stable in neutral or alkaline solutions. 3,4-End DKGL suppressed more strongly the linoleic acid (LA) peroxidation in the medium containing 20% EtOH and 10 mM LA than did AsA. This may suggest the possibility that 3,4-End DKGL reproduces AsA from DHA in physiological status. |
| Databáze: | OpenAIRE |
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