Introducing height to mechanobiology

Autor:	Jip Zonderland
Přispěvatelé:	Moroni, Lorenzo, van Blitterswijk, Clemens, RS: MERLN - Complex Tissue Regeneration (CTR), CTR
Rok vydání:	2020
Předmět:	Engineering business.industry Perspective (graphical) regenerative medicine cytoskeleton 3D printing Regenerative medicine Mechanobiology Tissue engineering tissue engineering 3D biology business Neuroscience
Popis:	Cell behavior is relatively well studied in 2D petridishes, but not in a 3D environment. Increasing evidence shows a large difference in cell behavior in 3D vs 2D. This thesis is focussed on exploring the extent and consequences of these differences in tissue stiff engineering scaffolds. A large influence of the 3D environment on mechanobiological proteins was found and it was shown that these proteins have a different role in 3D than in 2D. On top of this, several novel scaffolds were developed that can help to advance 3D biological research.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af273d06e8b37541872aa93dded658d https://doi.org/10.26481/dis.20200701jz Zobrazit plný text záznamu