A longitudinal retrospective analysis of left ventricular mass in a cohort of pediatric kidney transplant recipients

Autor:	Lorraine A. Hamiwka, Deborah Fruitman, Robyn McLaughlin, Susan Samuel, Silviu Grisaru
Rok vydání:	2014
Předmět:	Male Pediatrics medicine.medical_specialty Adolescent Left ventricular hypertrophy Single Center Prevalence Humans Medicine Postoperative Period Child Prospective cohort study Kidney transplantation Retrospective Studies Ultrasonography Transplantation business.industry Infant Newborn Infant medicine.disease Kidney Transplantation Surgery Treatment Outcome Child Preschool Preoperative Period Pediatrics Perinatology and Child Health Cohort Ambulatory Kidney Failure Chronic Female Hypertrophy Left Ventricular business Follow-Up Studies Kidney disease
Zdroj:	Pediatric Transplantation. 18:810-815
ISSN:	1397-3142
DOI:	10.1111/petr.12365
Popis:	Childhood end-stage kidney disease is associated with increased risk for early adulthood cardiovascular (CV) morbidity and mortality. Increased LVM is an early indicator of CV disease. Previous studies have suggested that LVM decreases after kidney transplantation; however, trends have been inconsistent. A single center retrospective longitudinal cohort analysis of LVM, documented annually, starting before kidney transplantation for up to 10 yr after transplantation was performed. BP documented by annual 24-h ambulatory monitoring studies, and BMI values were also reviewed. Twenty-seven children followed for a mean period of 5.3 yr were included. Depending on definition of LVH, its prevalence pretransplant and in the first years post-transplant was up to 33% dropping to 0-25% thereafter. Individual longitudinal LVM z-score trends were highly variable but generally trended toward the mean immediately after transplant and toward negative values in the following years. BP was stable during the follow-up period while mean annual BMI increased in the first-year post-transplant but declined thereafter. In a cohort of pediatric renal transplant recipients, prevalence of LVH decreased after transplant; however, individual longitudinal LVM trends were highly variable among patients. Prospective studies are needed to correlate individual LVM trends with outcomes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af1475420ea018d55c55ef4d566d41c https://doi.org/10.1111/petr.12365 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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