The Relation Between Posttraumatic Stress Symptom Severity and Startle Potentiation to Predictable and Unpredictable Threat
| Autor: | Stewart A. Shankman, Huiting Liu, Erin C. Berenz, Stephanie M. Gorka, Carter J. Funkhouser, Lynne Lieberman, K. Luan Phan, Kelly A. Correa |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Reflex Startle business.industry Uncertainty Symptom severity Fear Anxiety 030227 psychiatry Stress Disorders Post-Traumatic Young Adult 03 medical and health sciences Psychiatry and Mental health Posttraumatic stress 0302 clinical medicine Treatment targets Humans Medicine Female Reactivity (psychology) business 030217 neurology & neurosurgery Startle potentiation Clinical psychology |
| Zdroj: | Journal of Nervous & Mental Disease. 208:397-402 |
| ISSN: | 1539-736X 0022-3018 |
| Popis: | Aberrant threat reactivity has been implicated in the pathophysiology of posttraumatic stress disorder (PTSD); however, the literature on this association is mixed. One factor that may contribute to this inconsistent association is differences in severity of posttraumatic stress symptoms (PTSSs) across studies, but no studies have tested this hypothesis. The relation between PTSD and threat reactivity may also differ between unpredictable threats (U-threats) and predictable threats (P-threats), given burgeoning evidence to support a particular role for aberrant responding to U-threat in PTSD. The present study examined how PTSS severity relates to startle potentiation to U-threat and P-threat in a trauma-exposed community sample (N = 258). There was a negative linear, but not quadratic, relation between PTSS severity and startle potentiation to U-threat, but not P-threat. Blunted defensive responding to U-threat may therefore contribute to higher levels of PTSSs and may represent a novel treatment target for higher levels of PTSSs. |
| Databáze: | OpenAIRE |
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