pH control of the electrostatic binding of gold and iron oxide nanoparticles to tobacco mosaic virus
Autor: | Christina Wege, Eoin K. Fox, Alexander M. Bittner, Elizaveta Nikulina, Dermot F. Brougham, Abid Ali Khan, M Ł Górzny |
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Rok vydání: | 2013 |
Předmět: |
viruses
Ph control Nanoparticle Metal Nanoparticles Protonation 02 engineering and technology 010402 general chemistry Photochemistry 01 natural sciences Ferric Compounds chemistry.chemical_compound Electrochemistry Tobacco mosaic virus General Materials Science Spectroscopy Chemistry fungi Wild type food and beverages Chemical modification Surfaces and Interfaces Hydrogen-Ion Concentration 021001 nanoscience & nanotechnology Condensed Matter Physics 3. Good health 0104 chemical sciences Tobacco Mosaic Virus Biochemistry Gold 0210 nano-technology Iron oxide nanoparticles Cysteine |
Zdroj: | Langmuir |
ISSN: | 1520-5827 |
Popis: | We report the binding of nanoparticles (NPs) to wild type (unmodified) tobacco mosaic virus (TMV). The viruses are simply mixed with citrate-coated, negatively charged gold and iron oxide nanoparticles (IONPs) in acidic solution. This results in TMV decorated along its whole length by the respective particles. Such a decoration usually requires chemical modification or mutation of TMV (e.g., cysteine residues), but here we simply reduce TMV’s natural negative charge by protonation. The particles are protonated to a much smaller extent. This charge-based mechanism does not operate for neutral particles. |
Databáze: | OpenAIRE |
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