Frozen Cytology of Meningeal Malignant Solitary Fibrous Tumor/Hemangiopericytoma
| Autor: | Gie Taek Yie, Na Rae Kim, Myunghee Kang, Dong Hae Chung |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Round cells Pathology medicine.medical_specialty Solitary fibrous tumor Histology Frozen Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Cytology lcsh:Pathology medicine Brain magnetic resonance imaging Pseudoalveolar Pattern Hemangiopericytoma Solitary fibrous tumors Case Study business.industry Malignant Solitary Fibrous Tumor medicine.disease 030104 developmental biology Central nervous system 030220 oncology & carcinogenesis Mitotic Figure business lcsh:RB1-214 |
| Zdroj: | Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine, Vol 53, Iss 3, Pp 192-197 (2019) |
| ISSN: | 2383-7837 |
| Popis: | A 51-year-old woman presented with severe dizziness. The brain magnetic resonance image revealed a 5.5 cm multiloculated mass with a thick rim in the left temporal lobe. Cytological examination of frozen diagnosis of the mass showed hypercellular sheets of round and rhabdoid cells in a hemorrhagic background, and two mitotic figures were observed. Histologically, the excised dura-based mass consisted of predominantly round cells with small foci of rhabdoid tumor cells in a pseudoalveolar pattern in a hemorrhagic background, and the cells showed nuclear positivity for signal transducer and activator of transcription 6 as well as frequent mitosis. The mass was diagnosed as a grade 3 solitary fibrous tumor (SFT)/hemangiopericytoma (HPC). The cytological diagnosis of SFT/HPC is challenging because of the heterogeneous cytological findings, such as histological heterogeneity, and because there are no standardized cytological criteria for malignant SFT/HPC. Cytological findings, such as singly scattered small cells, hypercellularity, rare ropy collagen, and round and rhabdoid cells with pseudoalveolar pattern, may assist in the diagnosis of malignant SFT/HPC. |
| Databáze: | OpenAIRE |
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