A randomised, controlled study on the effects of a short-term endurance training programme in patients with major depression * Commentary
| Autor: | K Knubben, F M Reischies, M Adli, P Schlattmann, M Bauer, F Dimeo, L Ansley |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Physical Therapy Sports Therapy and Rehabilitation Placebo Severity of Illness Index law.invention Randomized controlled trial Endurance training law Severity of illness Humans Medicine Orthopedics and Sports Medicine Prospective Studies Prospective cohort study Depression (differential diagnoses) Psychiatric Status Rating Scales Depressive Disorder Major business.industry General Medicine Middle Aged Center for Epidemiologic Studies Depression Scale Combined Modality Therapy Antidepressive Agents Exercise Therapy Treatment Outcome Mood Physical Endurance Physical therapy Female Original Article business |
| Zdroj: | British Journal of Sports Medicine. 41:29-33 |
| ISSN: | 0306-3674 |
| DOI: | 10.1136/bjsm.2006.030130 |
| Popis: | Objective: To evaluate the short-term effects of exercise in patients with major depression. Design: Prospective, randomised, controlled study. Setting: A university hospital. Patients: A consecutive series of 38 inpatients with a major depression episode undergoing standard clinical antidepressant drug treatment. Interventions: Patients were randomly assigned to an exercise (walking, n = 20) or placebo (low-intensity stretching and relaxation exercises, n = 18) group. Training was carried out for 10 days. Main outcome measurements: Severity of depression assessed with the Bech-Rafaelsen Melancholy Scale (BRMS) and the Center for Epidemiologic Studies Depression scale (CES-D). Results: After 10 days, reduction of depression scores in the exercise group was significantly larger than in the placebo group (BRMS: 36% v 18%; CES-D: 41% v 21%; p for both = 0.01); the proportion of patients with a clinical response (reduction in the BRMS scores by more than six points) was also larger for the exercise group (65% v 22%, p Conclusions: Endurance exercise may help to achieve substantial improvement in the mood of selected patients with major depression in a short time. |
| Databáze: | OpenAIRE |
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