Gastrointestinal and Skin Lesions in Piglets Naturally Infected with Pseudorabies Virus
| Autor: | Yoshihide Usami, Satomi Nagai, Minoru Narita, Kazuhiko Tajima, Kenji Kawashima, Hideo Komaniwa, Kazuhiko Ezura |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Necrosis Swine 040301 veterinary sciences viruses animal diseases Myenteric Plexus Pseudorabies Connective tissue Biology Epithelium Virus 0403 veterinary science Lesion 03 medical and health sciences Ballooning degeneration Intestine Small medicine Animals Antigens Viral Myenteric plexus Skin Neurons Swine Diseases Hematoma Gastrointestinal tract integumentary system General Veterinary Stomach 04 agricultural and veterinary sciences biology.organism_classification Herpesvirus 1 Suid Immunohistochemistry 030104 developmental biology medicine.anatomical_structure Animals Newborn Nerve Degeneration medicine.symptom Digestive System |
| Zdroj: | Journal of Veterinary Diagnostic Investigation. 7:451-455 |
| ISSN: | 1943-4936 1040-6387 |
| DOI: | 10.1177/104063879500700405 |
| Popis: | Pseudorabies virus (PRV) infection was diagnosed in 4 piglets from a litter by immunohistopathologic examination and virus isolation. Three piglets had moderate to severe neuronal degeneration, and PRV antigen was detected in Auerbach's myenteric plexus and Meissner's submucosal plexus of the gastrointestinal tract. One piglet had 2 types of skin lesions. One lesion appeared on the hip and ear and was characterized by ballooning degeneration, necrosis of epithelial cells, and intranuclear inclusion bodies. The other was found on the ear and hematoma-like lesion and was composed of fibrinoid exudation and degenerative connective tissue. PRV antigen was clearly demonstrated in both skin lesions. These results suggested that degeneration of myenteric plexuses might be another characteristic of lesions in PRV-infected pigs and that the virus spreads by interaction between the skin and myenteric plexuses to the central nervous system. |
| Databáze: | OpenAIRE |
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