Catalytic Dehydration of Fructose to 5-Hydroxymethylfurfural (HMF) in Low-Boiling Solvent Hexafluoroisopropanol (HFIP)
| Autor: | Ulf Prüße, Linda Teevs, Eric Weingart, Sarah Tschirner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Propanols
Pharmaceutical Science Alcohol Fructose 010402 general chemistry 01 natural sciences Article Catalysis Analytical Chemistry law.invention ion-exchange resin lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry law Drug Discovery medicine Furaldehyde Dehydration Physical and Theoretical Chemistry Particle Size Ion-exchange resin HMF Distillation HFIP Molecular Structure 010405 organic chemistry Chemistry Organic Chemistry Temperature medicine.disease 0104 chemical sciences Solvent Kinetics Chemistry (miscellaneous) Yield (chemistry) Solvents Molecular Medicine Ion Exchange Resins Nuclear chemistry Lewatit K2420 |
| Zdroj: | Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry Molecules Volume 23 Issue 8 Molecules, Vol 23, Iss 8, p 1866 (2018) |
| ISSN: | 1420-3049 |
| Popis: | A mixture of hexafluoroisopropanol (HFIP) and water was used as a new and unknown monophasic reaction solvent for fructose dehydration in order to produce HMF. HFIP is a low-boiling fluorous alcohol (b.p. 58 ° C). Hence, HFIP can be recovered cost efficiently by distillation. Different ion-exchange resins were screened for the HFIP/water system in batch experiments. The best results were obtained for acidic macroporous ion-exchange resins, and high HMF yields up to 70% were achieved. The effects of various reaction conditions like initial fructose concentration, catalyst concentration, water content in HFIP, temperature and influence of the catalyst particle size were evaluated. Up to 76% HMF yield was attained at optimized reaction conditions for high initial fructose concentration of 0.5 M (90 g/L). The ion-exchange resin can simply be recovered by filtration and reused several times. This reaction system with HFIP/water as solvent and the ion-exchange resin Lewatit K2420 as catalyst shows excellent performance for HMF synthesis. |
| Databáze: | OpenAIRE |
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