Furosemide infusion in children with dengue fever and hypoxemia
Autor: | G. V. Basavaraja, K. R. Bharath Kumar Reddy, Shivananda |
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Rok vydání: | 2014 |
Předmět: |
ARDS
medicine.medical_specialty Adolescent Treatment outcome India Acute respiratory distress Research Brief Hypoxemia Dengue fever Dengue Furosemide Pediatric surgery Humans Medicine Prospective Studies Diuretics Child Infusions Intravenous Prospective cohort study Outcome Respiratory Distress Syndrome business.industry Infant medicine.disease Treatment Outcome Child Preschool Anesthesia Pediatrics Perinatology and Child Health medicine.symptom business medicine.drug |
Zdroj: | Indian Pediatrics |
ISSN: | 0974-7559 0019-6061 |
DOI: | 10.1007/s13312-014-0398-8 |
Popis: | Objectives To study the role of furosemide infusion in the management of Acute respiratory distress syndrome (ARDS) associated with dengue fever. Methods Children between the ages of 1 month to 18 years, who fulfilled the WHO clinical criteria for dengue infection and American European Consensus Criteria criteria for ARDS with Dengue IgM positivity, were evaluated. Patients were studied as group D (receiving diuretic therapy alone) and group B (both ventilation and diuretics), and compared to a historical control group V (ventilation alone). Furosemide infusion was administered at 0.05–0.1 mg/kg/hour for 48 hours, maintaining a urine output of 2–4 mL/kg/hour. Results There was a significant difference in survival in the three groups. Significant difference was noted between pre- and postintervention arterial blood gases with respect to PCO2 (P=0.02), pO2 (P=0.003), PaO2/FaO2 ratio (P |
Databáze: | OpenAIRE |
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