An engineered virus as a scaffold for three-dimensional self-assembly on the nanoscale
| Autor: | Carissa M. Soto, Amy Szuchmacher Blum, Paul D. Franzon, Terence L. Schull, Anju Chatterji, C.J. Amsinck, Charmaine D. Wilson, Banahalli R. Ratna, John E. Johnson, Tina Louise Brower, Ranganathan Shashidhar, Steven K. Pollack, Tianwei Lin |
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| Rok vydání: | 2006 |
| Předmět: |
Models
Molecular Scaffold Materials science Nanostructure viruses Biomedical Engineering Nanoparticle Nanotechnology Protein Engineering Nanocomposites Biomaterials Molecular wire Capsid Viral scaffold Microscopy Scanning Tunneling General Materials Science biology Cowpea mosaic virus General Chemistry biology.organism_classification Nanostructures Models Chemical Colloidal gold Mutation Viruses Self-assembly Electronics Biotechnology |
| Zdroj: | Small (Weinheim an der Bergstrasse, Germany). 1(7) |
| ISSN: | 1613-6829 |
| Popis: | Exquisite control over positioning nanoscale components on a protein scaffold allows bottom-up self-assembly of nanodevices. Using cowpea mosaic virus, modified to express cysteine residues on the capsid exterior, gold nanoparticles were attached to the viral scaffold to produce specific interparticle distances (see picture). The nanoparticles were then interconnected using thiol-terminated conjugated organic molecules that act as "molecular wires", resulting in a 3D spherical conductive network, which is only 30 nm in diameter. |
| Databáze: | OpenAIRE |
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