Polypharmacy Among Older Brazilians: Prevalence, Factors Associated and Sociodemographic Disparities (ELSI-Brazil)
| Autor: | Brayan V. Seixas, Gabriel R. Freitas |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Longitudinal study
Multivariate analysis mesh:Multivariate Analysis Cross-sectional study cross-sectional studies lcsh:RS1-441 Pharmaceutical Science Pharmacy mesh:Socioeconomic Factors 030226 pharmacology & pharmacy Health Services Accessibility 0302 clinical medicine mesh:Polypharmacy mesh:Brazil Prevalence Medicine mesh:Age Factors mesh:Sex Factors Original Research education.field_of_study Age Factors Race Factors multivariate analysis race factors brazil mesh:Prevalence symbols Brazil age factors medicine.medical_specialty multimorbidity prevalence Population socioeconomic factors lcsh:Pharmacy and materia medica 03 medical and health sciences symbols.namesake mesh:Race Factors Sex Factors mesh:Health Services Accessibility Poisson regression polypharmacy education Polypharmacy business.industry mesh:Multimorbidity Public health lcsh:RM1-950 Multimorbidity sex factors lcsh:Therapeutics. Pharmacology Cross-Sectional Studies Socioeconomic Factors mesh:Cross-Sectional Studies Multivariate Analysis health services accessibility business Body mass index Demography |
| Zdroj: | Pharmacy Practice Pharmacy Practice (Granada) v.19 n.1 2021 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname SciELO España: Revistas Científicas Españolas de Ciencias de la Salud Instituto de Salud Carlos III (ISCIII) Pharmacy Practice, Vol 19, Iss 1, p 2168 (2021) |
| DOI: | 10.21203/rs.3.rs-54644/v1 |
| Popis: | Background: Polypharmacy has become an increasingly public health issue as population age and novel drugs are developed. Yet, evidence on low- and middle-income countries (LMIC) is still scarce. Objective: This work aims to estimate the prevalence of polypharmacy among Brazilians aged 50 and over, and investigate associated factors. Methods: A cross-sectional study was conducted using data from the baseline assessment of the Brazilian Longitudinal Study of Aging (ELSI-Brazil), a nationally representative study of persons aged 50 years and older (n=9,412). Univariate and bivariate analyses described the sample. Robust Poisson regression was used to estimate prevalence ratios and predict probabilities of polypharmacy. Results: Prevalence of polypharmacy was estimated at 13.5% among older adults in Brazil. Important disparities were observed in regard to gender (16.1% among women and 10.5% among men), race (16.0% among whites and 10.1% among blacks) and geographic region (ranging from 5.1% in the North to 18.7% in the South). The multivariate analysis showed that polypharmacy is associated with various sociodemographic/individual factors (age, gender, race, education, region, health status, body mass index) as well as with several variables of healthcare access/utilization (number of visits, same physician, provider’s knowledge of patient’s medications, gate-keeper, and difficulty managing own medication). Overall, the more utilization of health services, the higher the probability of polypharmacy, after adjusting for all other model covariates. Conclusions: Polypharmacy prevalence is relatively low in Brazil, compared to European countries. After controlling for variables of healthcare need and demographic characteristics, there is still substantial residual variance in polypharmacy prevalence. Policies to identify inappropriate prescribing and reduce regional discrepancies are necessary. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|