Molecular Diagnostics in the Evaluation of Pancreatic Cysts
| Autor: | Aatur D. Singhi, Abigail I. Wald, Brian K. Theisen |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Pathology and Forensic Medicine Proto-Oncogene Proteins p21(ras) 03 medical and health sciences 0302 clinical medicine Abdominal scans Pancreatic Pseudocyst parasitic diseases Biomarkers Tumor Chromogranins GTP-Binding Protein alpha Subunits Gs medicine Humans Cyst Pathology Molecular Neoplasm Staging Incidental Findings Intraductal papillary mucinous neoplasm business.industry Prognosis Serous Cystadenoma medicine.disease Molecular diagnostics Adenocarcinoma Mucinous Carcinoma Papillary Pancreatic Neoplasms medicine.anatomical_structure 030220 oncology & carcinogenesis Adenocarcinoma 030211 gastroenterology & hepatology Surgery Pancreatic Cyst Pancreatic cysts Pancreas business Carcinoma Pancreatic Ductal |
| Zdroj: | Surgical Pathology Clinics. 9:441-456 |
| ISSN: | 1875-9181 |
| Popis: | Within the past few decades, there has been a dramatic increase in the detection of incidental pancreatic cysts. It is reported a pancreatic cyst is identified in up to 2.6% of abdominal scans. Many of these cysts, including serous cystadenomas and pseudocysts, are benign and can be monitored clinically. In contrast, mucinous cysts, which include intraductal papillary mucinous neoplasms and mucinous cystic neoplasms, have the potential to progress to pancreatic adenocarcinoma. In this review, we discuss the current management guidelines for pancreatic cysts, their underlying genetics, and the integration of molecular testing in cyst classification and prognostication. |
| Databáze: | OpenAIRE |
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