Plasma Levels of Soluble P-Selectin, Beta-Thromboglobulin and Platelet Indices in Patients With Prediabetes: Effects of Acute Hyperglycemic Stress

Autor:	Nesibe Esra YAŞAR, Dildar KONUKOĞLU
Rok vydání:	2021
Předmět:	Metabolic Syndrome Risk mean platelet volume Coagulation Volume Endocrinology Diabetes and Metabolism Activation Platelet Activation Atherosclerosis Prognosis prediabetic state Distribution Width Glucose Internal Medicine Diabetes-Mellitus hyperglycemia
Zdroj:	The Turkish Journal of Endocrinology and Metabolism. 25:174-183
ISSN:	1308-9846 1301-2193
DOI:	10.25179/tjem.2020-79546
Popis:	Objective: To examine the effects of acute hyperglycemic stress on platelet activation by analyzing the plasma levels of P-selectin, beta-thromboglobulin, and platelet indices in an oral glucose tolerance test (OGTT). Material and Methods: The OGTT results were used to form four study groups: a control group (n=31) and a prediabetic group (n=103) comprising three subgroups according to the American Diabetes Association criteria for diabetes. Platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) were determined using the impedance method, and P-selectin and beta-thromboglobulin (beta-TG) levels were determined by enzyme-linked immunosorbent assay. P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab38cfc406ed2ba564791563dc1ba5d https://doi.org/10.25179/tjem.2020-79546 Zobrazit plný text záznamu