Vasculitis attributed to the nicotine patch (Nicotinell)

Autor:	E. Van Hillo, E.P.M. Bolsius, M. M. Van Der Klauw, W.H.H.W. Van Den Berg, F.F.J.M. Sutorius, Bruno H. Stricker
Rok vydání:	1996
Předmět:	medicine.medical_specialty Erythema medicine.diagnostic_test business.industry Nicotine patch medicine.medical_treatment Arthritis Craving Dermatology medicine.disease Surgery Nicotine Skin biopsy Medicine Generalized erythema medicine.symptom business Vasculitis medicine.drug
Zdroj:	British Journal of Dermatology. 134:361-364
ISSN:	1365-2133 0007-0963
Popis:	Nicotine-containing patches are used to facilitate tobacco withdrawal by mitigating abstinence symptoms and diminishing craving. We describe two patients who developed vasculitis in association with the use of a nicotine patch. The first concerns a patient who developed fever, arthritis, a generalized erythema and purpuric lesions, after 3 days use of nicotine patches. Laboratory results and a skin biopsy confirmed the diagnosis of a leucocytoclastic vasculitis. After stopping use of the patch, the patient recovered. On challenge, the symptoms reappeared. The second patient developed purpuric lesions during the use of nicotine patches, and recovered fully after these were stopped. In these patients, nicotine patches seem to be causally related to the development of vasculitis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab0f5a2d72525e72d174f857967b469 https://doi.org/10.1046/j.1365-2133.1996.05726.x Zobrazit plný text záznamu Plný text