Efficacy of Various Mitigation Devices in Reducing Fugitive Emissions from Nebulizers
| Autor: | James B Fink, Jie Li, Rajiv Dhand, Amnah Alolaiwat, Guoqiang Jing, Lauren Harnois |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Aerosols
Pulmonary and Respiratory Medicine business.industry Nebulizers and Vaporizers Masks Ethics committee Small volume nebulizer Equipment Design General Medicine Critical Care and Intensive Care Medicine Bronchodilator Agents Aerosol Clinical Practice Nebulizer Administration Inhalation Humans Medicine Albuterol Fugitive emissions business Vibrating mesh nebulizer Mouthpiece Biomedical engineering |
| Zdroj: | Respiratory Care. 67:394-403 |
| ISSN: | 1943-3654 0020-1324 |
| Popis: | Introduction: Fugitive aerosol concentrations generated by different nebulizers and interfaces in vivo, and mitigation of aerosol dispersion into the environment with various commercially available devices are not known. Methods: Nine healthy volunteers were given 3 mL saline with a small volume nebulizer (SVN) or vibrating mesh nebulizer (VMN) with a mouthpiece, a mouthpiece with an exhalation filter, an aerosol mask with open ports for SVN and a valved facemask for VMN, and a facemask with a scavenger (Exhalo) in random order. Five of the participants received treatments using a face tent scavenger (Vapotherm) and a mask with exhalation filter with SVN and VMN in a random order. Treatments were performed in an ICU room, with 2 particle counters positioned 1 and 3 feet from participants measuring aerosol concentrations at sizes of 0.3-10 µm at baseline, before, during and after each treatment. The Ethics Committee at Rush University approved this study. Results: Fugitive aerosol concentrations were higher with SVN than VMN and higher with a facemask than a mouthpiece. Adding an exhalation filter to a mouthpiece reduced aerosol concentrations of 0.3-1.0 µm in size for VMN and 0.3-3.0 µm for SVN (all p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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