Sacral spinal interneurones and the control of urinary bladder and urethral striated sphincter muscle function
| Autor: | S. J. Shefchyk |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Sacrum
Physiology media_common.quotation_subject Urinary Bladder Inhibitory postsynaptic potential Urination Lumbar Urethra Interneurons Animals Medicine Topical Review Muscle Skeletal media_common Urinary bladder business.industry Urethral sphincter Ganglia Parasympathetic Anatomy musculoskeletal system Spinal cord Electrophysiology medicine.anatomical_structure Spinal Cord nervous system Excitatory postsynaptic potential business |
| Zdroj: | The Journal of Physiology. 533:57-63 |
| ISSN: | 1469-7793 0022-3751 |
| DOI: | 10.1111/j.1469-7793.2001.0057b.x |
| Popis: | Normally, during bladder filling (continence) and expulsion (micturition) there is a reciprocity between the pattern of activity in the urinary bladder sacral parasympathetic efferents and the somatic motoneurones innervating the striated external urethral sphincter muscle. The co-ordination of this pattern of reciprocal activity appears to be determined by excitatory and inhibitory actions of a variety of segmental afferents and descending systems with sacral spinal actions. These actions may in part be mediated through lower lumbar and sacral excitatory and inhibitory spinal interneurones. Over the past 30 years, both neuroanatomical and electrophysiological approaches have been used to reveal an ever-increasing richness in the neuronal network in the lower spinal cord related to the bladder and striated external urethral sphincter muscle. The purpose of this review is to present an overview of the identified excitatory and inhibitory spinal interneurones hypothesized to be involved in the central networks controlling the sacral bladder parasympathetic preganglionic neurones and striated urethral sphincter motoneurones during continence and micturition. |
| Databáze: | OpenAIRE |
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