Transperineal laser ablation for percutaneous treatment of benign prostatic hyperplasia: a feasibility study. Results at 6 and 12 months from a retrospective multi-centric study

Autor: Gianluigi Patelli, Renato Esposito, Gennaro Iapicca, Giovanni Mauri, Colleen P. Ryan, Guglielmo Manenti, Tommaso Perretta, Claudio Maurizio Pacella
Rok vydání: 2019
Předmět:
Zdroj: Prostate Cancer and Prostatic Diseases. 23:356-363
ISSN: 1476-5608
1365-7852
DOI: 10.1038/s41391-019-0196-4
Popis: To investigate the effectiveness and safety of SoracteLite™—transperineal percutaneous laser ablation (TPLA) in the treatment of patients with symptomatic benign prostatic hyperplasia (BPH) at 6 and 12 months follow-up. Patients with urinary symptoms secondary to BPH underwent TPLA under local anesthesia in four centers. Under US guidance, up to four 21G applicators were inserted in the prostatic tissue. Each treatment was performed with diode laser operating at 1064 nm changing the illumination time according to prostate size. The primary end-points of this study were change in IPSS, PVR, Qmax, QoL, and prostatic volume at 6 an 12 months from SoracteLiteTM TPLA treatment. Secondary end-point was the assessment of complications. Analysis was performed on data 160 patients (mean age 69.8 ± 9.6 years) with at least 6 months follow and of 83 patients (mean age 67.9 ± 8.7 years) with at least 12 months follow-up. At 6 months, IPSS improved from 22.5 ± 5.1 to 7.7 ± 3.3 (P
Databáze: OpenAIRE
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