Zinc-Air Battery-Based Self-Powered Sensor with High Output Power for Ultrasensitive MicroRNA let-7a Detection in Cancer Cells

Autor:	Yunxia Jin, Zhen Wu, Li Li, Ruiqiang Yan, Junlun Zhu, Wei Wen, Xiuhua Zhang, Shengfu Wang
Rok vydání:	2022
Předmět:	Oxygen Glucose Oxidase MicroRNAs Zinc Electric Power Supplies Neoplasms Benzene Metal-Organic Frameworks Analytical Chemistry
Zdroj:	Analytical Chemistry. 94:14368-14376
ISSN:	1520-6882 0003-2700
DOI:	10.1021/acs.analchem.2c03093
Popis:	Self-powered sensors do not require a power supply and are easy to miniaturize, which have potential for constructing wearable, portable, and real-time detection devices. However, it is challenging for the detection of low abundant targets due to the low output power density of fuel cells and much interference of complex biological environment. Herein, a new kind of photocatalytic zinc-air battery-based self-powered electrochemical sensor (ZAB-SPES) was constructed for the detection of microRNA let-7a (miRNA let-7a) by combining magnetic nanobeads (MBs) with a metal-organic framework loaded with glucose oxidase (MOFs@GOX). Poly(1,4-di(2-thienyl))benzene (PDTB) was used as the photocathode material, and the proposed ZAB-SPES had a high power density of 22.8 μW/cm
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9eac23f0f69401ad591d22aedded9f https://doi.org/10.1021/acs.analchem.2c03093 Zobrazit plný text záznamu